Validated Bayesian Differentiation of Causative and Passenger Mutations
نویسندگان
چکیده
منابع مشابه
Validated Bayesian Differentiation of Causative and Passenger Mutations
In many contexts, the problem arises of determining which of many candidate mutations is the most likely to be causative for some phenotype. It is desirable to have a way to evaluate this probability that relies as little as possible on previous knowledge, to avoid bias against discovering new genes or functions. We have isolated mutants with blocked cell cycle progression in Chlamydomonas and ...
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ژورنال
عنوان ژورنال: G3 Genes|Genomes|Genetics
سال: 2017
ISSN: 2160-1836
DOI: 10.1534/g3.117.039016